Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mast/stem cell growth factor receptor Kit [V560G,D816V]' and Ligand = 'BDBM175667'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit [V560G,D816V] (Homo sapiens (Human))	BDBM175667 (US9688680, 213) Show SMILES Cc1ccc(CNC(=O)C2CN(C2)c2ncnn3cc(cc23)-c2ccc(cc2)C2(O)CCOC2)cc1 Show InChI InChI=1S/C28H29N5O3/c1-19-2-4-20(5-3-19)13-29-27(34)23-14-32(15-23)26-25-12-22(16-33(25)31-18-30-26)21-6-8-24(9-7-21)28(35)10-11-36-17-28/h2-9,12,16,18,23,35H,10-11,13-15,17H2,1H3,(H,29,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	25
BLUEPRINT MEDICINES CORPORATION US Patent					Assay Description 10,000 HMC1.2 cells were incubated in 22 ul culture media (phenol-red free IMDM, no serum) in each well of a 384-well plate and serum starved overnig...				US Patent US9688680 (2017) BindingDB Entry DOI: 10.7270/Q2NV9GDQ
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