Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Maternal embryonic leucine zipper kinase' and Ligand = 'BDBM166168'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM166168 (US9067937, 216) Show SMILES CC(C)C(=O)c1cnc2ccc(nc2c1N[C@H]1CC[C@H](CN(C)C)CC1)-c1cc(Cl)c(O)c(Cl)c1 |r,wU:19.21,wD:16.17,(7.34,-2.7,;6,-3.47,;6,-5.01,;4.67,-2.7,;4.67,-1.16,;3.33,-3.47,;3.33,-5.01,;2,-5.78,;.67,-5.01,;-.67,-5.78,;-2,-5.01,;-2,-3.47,;-.67,-2.7,;.67,-3.47,;2,-2.7,;2,-1.16,;.91,-.07,;1.31,1.42,;.22,2.51,;-1.27,2.11,;-2.36,3.2,;-1.96,4.69,;-3.05,5.78,;-.47,5.09,;-1.66,.62,;-.58,-.47,;-3.33,-2.7,;-4.67,-3.47,;-6,-2.7,;-7.34,-3.47,;-6,-1.16,;-7.34,-.39,;-4.67,-.39,;-4.67,1.15,;-3.33,-1.16,)| Show InChI InChI=1S/C27H32Cl2N4O2/c1-15(2)26(34)19-13-30-23-10-9-22(17-11-20(28)27(35)21(29)12-17)32-25(23)24(19)31-18-7-5-16(6-8-18)14-33(3)4/h9-13,15-16,18,35H,5-8,14H2,1-4H3,(H,30,31)/t16-,18-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.90	n/a	n/a	n/a	n/a	7.4	25
OncoTherapy Science, Inc. US Patent					Assay Description MELK activity was determined in the presence or absence of compounds using fluorescein isothiocyanate-labeled (FITC-labeled) histone H3 peptide as a ...				US Patent US9067937 (2015) BindingDB Entry DOI: 10.7270/Q2BR8QX4
					More data for this Ligand-Target Pair