Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Maternal embryonic leucine zipper kinase' and Ligand = 'BDBM177103'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM177103 (US9120749, 469) Show SMILES CN1CCN(CC1)c1ccc(Nc2c(cnc3ccc(cc23)-c2cnc(nc2)C#N)C(=O)C2CC2)cn1 Show InChI InChI=1S/C28H26N8O/c1-35-8-10-36(11-9-35)26-7-5-21(16-33-26)34-27-22-12-19(20-14-31-25(13-29)32-15-20)4-6-24(22)30-17-23(27)28(37)18-2-3-18/h4-7,12,14-18H,2-3,8-11H2,1H3,(H,30,34)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	7.4	25
ONCOTHERAPY SCIENCE, INC. US Patent					Assay Description MELK activity was determined in the presence or absence of compounds using fluorescein isothiocyanate-labeled (FITC-labeled) histone H3 peptide as a ...				US Patent US9120749 (2015) BindingDB Entry DOI: 10.7270/Q2FX7872
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