Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Maternal embryonic leucine zipper kinase' and Ligand = 'BDBM177309'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM177309 (US9120749, 675) Show SMILES Oc1c(F)cc(cc1Cl)-c1ccc2ncc(C(=O)C3CC3)c(NC3CCC(CC3)N3CCC(F)(F)C3)c2c1 |(-7.44,-.11,;-6.1,-.88,;-6.1,-2.42,;-7.44,-3.19,;-4.77,-3.19,;-3.44,-2.42,;-3.44,-.88,;-4.77,-.11,;-4.77,1.43,;-2.1,-3.19,;-2.1,-4.73,;-.77,-5.5,;.56,-4.73,;1.9,-5.5,;3.23,-4.73,;3.23,-3.19,;4.56,-2.42,;4.56,-.88,;5.9,-3.19,;6.67,-4.52,;7.44,-3.19,;1.9,-2.42,;1.9,-.88,;.81,.21,;1.21,1.7,;.12,2.79,;-1.37,2.39,;-1.77,.9,;-.68,-.19,;-2.46,3.48,;-2.44,5.02,;-3.91,5.5,;-4.81,4.25,;-6.15,5.02,;-6.15,3.48,;-3.91,3,;.56,-3.19,;-.77,-2.42,)| Show InChI InChI=1S/C29H29ClF3N3O2/c30-23-12-18(13-24(31)28(23)38)17-3-8-25-21(11-17)26(22(14-34-25)27(37)16-1-2-16)35-19-4-6-20(7-5-19)36-10-9-29(32,33)15-36/h3,8,11-14,16,19-20,38H,1-2,4-7,9-10,15H2,(H,34,35)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	830	n/a	n/a	n/a	n/a	7.4	25
ONCOTHERAPY SCIENCE, INC. US Patent					Assay Description MELK activity was determined in the presence or absence of compounds using fluorescein isothiocyanate-labeled (FITC-labeled) histone H3 peptide as a ...				US Patent US9120749 (2015) BindingDB Entry DOI: 10.7270/Q2FX7872
					More data for this Ligand-Target Pair