Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Maternal embryonic leucine zipper kinase' and Ligand = 'BDBM177406'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM177406 (US9120749, 772) Show SMILES CC(=O)c1cnc2ccc(cc2c1N[C@H]1CC[C@H](CN2CCNCC2)CC1)-c1cc(Cl)c(O)c(Cl)c1 |r,wU:14.15,wD:17.19,(6.67,-3.97,;5.33,-3.2,;5.33,-1.66,;4,-3.97,;4,-5.51,;2.67,-6.28,;1.33,-5.51,;,-6.28,;-1.33,-5.51,;-1.33,-3.97,;,-3.2,;1.33,-3.97,;2.67,-3.2,;2.67,-1.42,;1.33,-.65,;,-1.42,;-1.33,-.65,;-1.33,.89,;-2.67,1.66,;-2.67,3.2,;-1.33,3.97,;-1.33,5.51,;-2.67,6.28,;-4,5.51,;-4,3.97,;,1.66,;1.33,.89,;-2.67,-3.2,;-2.67,-1.66,;-4,-.89,;-4,.65,;-5.33,-1.66,;-6.67,-.89,;-5.33,-3.2,;-6.67,-3.97,;-4,-3.97,)| Show InChI InChI=1S/C28H32Cl2N4O2/c1-17(35)23-15-32-26-7-4-19(20-13-24(29)28(36)25(30)14-20)12-22(26)27(23)33-21-5-2-18(3-6-21)16-34-10-8-31-9-11-34/h4,7,12-15,18,21,31,36H,2-3,5-6,8-11,16H2,1H3,(H,32,33)/t18-,21-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.10	n/a	n/a	n/a	n/a	7.4	25
ONCOTHERAPY SCIENCE, INC. US Patent					Assay Description MELK activity was determined in the presence or absence of compounds using fluorescein isothiocyanate-labeled (FITC-labeled) histone H3 peptide as a ...				US Patent US9120749 (2015) BindingDB Entry DOI: 10.7270/Q2FX7872
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