Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Matrilysin' and Ligand = 'BDBM26572'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrilysin (Homo sapiens (Human))	BDBM26572 ((3R,4R)-4-N-[4-({2-ethylpyrazolo[1,5-a]pyridin-3-y...) Show SMILES CCc1nn2ccccc2c1Cc1ccc(cc1)C(=O)N[C@@H]1CCOC[C@@H]1C(=O)NO |r| Show InChI InChI=1S/C23H26N4O4/c1-2-19-17(21-5-3-4-11-27(21)25-19)13-15-6-8-16(9-7-15)22(28)24-20-10-12-31-14-18(20)23(29)26-30/h3-9,11,18,20,30H,2,10,12-14H2,1H3,(H,24,28)(H,26,29)/t18-,20+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>6.37E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...				Bioorg Med Chem Lett 18: 1958-62 (2008) Article DOI: 10.1016/j.bmcl.2008.01.120 BindingDB Entry DOI: 10.7270/Q25B00SX
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