Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Matrix metalloproteinase-14' and Ligand = 'BDBM50348667'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM50348667 (CHEMBL1801057) Show SMILES COc1ccc(Oc2ccc(cc2)S(=O)(=O)C2(CCN(Cc3ccccn3)CC2)C(=O)NO)cc1 Show InChI InChI=1S/C25H27N3O6S/c1-33-20-5-7-21(8-6-20)34-22-9-11-23(12-10-22)35(31,32)25(24(29)27-30)13-16-28(17-14-25)18-19-4-2-3-15-26-19/h2-12,15,30H,13-14,16-18H2,1H3,(H,27,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human MMP14 assessed as cleavage of fluorogenic peptide MCAPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 by fluorometric assay				J Med Chem 53: 6653-80 (2010) Article DOI: 10.1021/jm100669j BindingDB Entry DOI: 10.7270/Q2KH0NQB
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