Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Matrix metalloproteinase-14' and Ligand = 'BDBM50437774'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM50437774 (CHEMBL2409687) Show SMILES C[C@]1(CS(=O)(=O)N2CCC(CC2)Oc2ccc(OCc3ccc(F)cc3)cc2)NC(=O)NC1=O |r| Show InChI InChI=1S/C23H26FN3O6S/c1-23(21(28)25-22(29)26-23)15-34(30,31)27-12-10-20(11-13-27)33-19-8-6-18(7-9-19)32-14-16-2-4-17(24)5-3-16/h2-9,20H,10-15H2,1H3,(H2,25,26,28,29)/t23-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.73E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP-14 using Mca-Pro-Leu-Ala-Nva-Dpa-Ala-Arg-NH2 as substrate after 20 hrs by fluorescence assay				Bioorg Med Chem Lett 23: 4705-12 (2013) Article DOI: 10.1016/j.bmcl.2013.05.089 BindingDB Entry DOI: 10.7270/Q2WS8VNH
					More data for this Ligand-Target Pair