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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Matrix metalloproteinase-17' and Ligand = 'BDBM400727'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Matrix metalloproteinase-17


(Homo sapiens (Human))		BDBM400727
PNG
(US10000476, Compound I-86)
Show SMILES Cc1cccn(CC2(NC(=O)NC2=O)c2ccc(Oc3ccccc3F)cc2)c1=O
Show InChI InChI=1S/C22H18FN3O4/c1-14-5-4-12-26(19(14)27)13-22(20(28)24-21(29)25-22)15-8-10-16(11-9-15)30-18-7-3-2-6-17(18)23/h2-12H,13H2,1H3,(H2,24,25,28,29)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/a 2.70E+4n/an/an/an/an/an/a



Universite degli Studi di Firenze



Assay Description
MMP-17: 90 μL (5.8 ng) of human MMP-17 (Calbiochem #475940) prepared with an assay buffer A was added to 90 μL of a 20 μM fluorescent ...

Bioorg Med Chem 17: 4503-9 (2009)


BindingDB Entry DOI: 10.7270/Q2V69MXD
More data for this
Ligand-Target Pair