BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Melanin-concentrating hormone receptor 1' and Ligand = 'BDBM50094882'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50094882
PNG
(CHEMBL3589135)
Show SMILES COc1cc(ccc1OCC(C)(C)O)N1Cc2cn(nc2C1=O)-c1ccc(Cl)cc1
Show InChI InChI=1S/C22H22ClN3O4/c1-22(2,28)13-30-18-9-8-17(10-19(18)29-3)25-11-14-12-26(24-20(14)21(25)27)16-6-4-15(23)5-7-16/h4-10,12,28H,11,13H2,1-3H3
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.17E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Research and Development

Curated by ChEMBL


Assay Description
Antagonist activity at human MCHR1 expressed in HEK293 cells assessed as inhibition of MCH-stimulated Ca2+ influx preincubated for 120 mins followed ...

Bioorg Med Chem Lett 25: 2793-9 (2015)


Article DOI: 10.1016/j.bmcl.2015.05.008
BindingDB Entry DOI: 10.7270/Q29C7053
More data for this
Ligand-Target Pair