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Found 1 hit Enz. Inhib. hit(s) with Target = 'Melanin-concentrating hormone receptor 1' and Ligand = 'BDBM50152497'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152497
PNG
(8-[1-(4-Isobutyl-phenyl)-pyrrolidin-3-yloxy]-quino...)
Show SMILES CC(C)Cc1ccc(cc1)N1CCC(C1)Oc1cccc2ccc(N)nc12
Show InChI InChI=1S/C23H27N3O/c1-16(2)14-17-6-9-19(10-7-17)26-13-12-20(15-26)27-21-5-3-4-18-8-11-22(24)25-23(18)21/h3-11,16,20H,12-15H2,1-2H3,(H2,24,25)
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Article
PubMed
n/an/a 1.20n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human Melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4883-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.035
BindingDB Entry DOI: 10.7270/Q2GB23H4
More data for this
Ligand-Target Pair