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Found 1 hit Enz. Inhib. hit(s) with Target = 'Melanin-concentrating hormone receptor 1' and Ligand = 'BDBM50152504'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50152504
PNG
(CHEMBL185266 | {8-[1-(4-Isobutyl-phenyl)-pyrrolidi...)
Show SMILES CC(C)Cc1ccc(cc1)N1CCC(C1)Oc1cccc2ccc(NCc3ccc(o3)-c3cccc(c3)C(F)(F)F)nc12
Show InChI InChI=1S/C35H34F3N3O2/c1-23(2)19-24-9-12-28(13-10-24)41-18-17-30(22-41)43-32-8-4-5-25-11-16-33(40-34(25)32)39-21-29-14-15-31(42-29)26-6-3-7-27(20-26)35(36,37)38/h3-16,20,23,30H,17-19,21-22H2,1-2H3,(H,39,40)
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PC sid
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Article
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n/an/a 41n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Concentration required to inhibit binding of [125I]-MCH radioligand to human Melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranes

Bioorg Med Chem Lett 14: 4883-6 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.035
BindingDB Entry DOI: 10.7270/Q2GB23H4
More data for this
Ligand-Target Pair