Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Melanin-concentrating hormone receptor 1' and Ligand = 'BDBM50186791'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50186791 (3-[4-(3'-cyano-biphenyl-4-yl)-1-cyclobutyl-piperid...) Show SMILES Fc1ccc(NC(=O)CCC2(CCN(CC2)C2CCC2)c2ccc(cc2)-c2cccc(c2)C#N)cc1F Show InChI InChI=1S/C31H31F2N3O/c32-28-12-11-26(20-29(28)33)35-30(37)13-14-31(15-17-36(18-16-31)27-5-2-6-27)25-9-7-23(8-10-25)24-4-1-3-22(19-24)21-34/h1,3-4,7-12,19-20,27H,2,5-6,13-18H2,(H,35,37)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human MCHR1 assessed as inhibition of MCH-mediated calcium ion influx by FLIPR assay				Bioorg Med Chem Lett 16: 3668-73 (2006) Article DOI: 10.1016/j.bmcl.2006.04.061 BindingDB Entry DOI: 10.7270/Q2251HT9
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