Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Melanin-concentrating hormone receptor 1' and Ligand = 'BDBM50192635'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50192635 (5,6-difluoro-N-((1R,3R,6R)-6-(3-((4-methylpiperazi...) Show SMILES CN1CCN(CCCN([C@@H]2CC[C@@]3(C[C@@H]3C2)c2cccc(CN3CCN(C)CC3)c2)c2nc3cc(F)c(F)cc3[nH]2)CC1 Show InChI InChI=1S/C34H47F2N7/c1-39-11-15-41(16-12-39)9-4-10-43(33-37-31-21-29(35)30(36)22-32(31)38-33)28-7-8-34(23-27(34)20-28)26-6-3-5-25(19-26)24-42-17-13-40(2)14-18-42/h3,5-6,19,21-22,27-28H,4,7-18,20,23-24H2,1-2H3,(H,37,38)/t27-,28+,34+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	321	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Binding activity against human MCH-R1				Bioorg Med Chem Lett 16: 5427-31 (2006) Article DOI: 10.1016/j.bmcl.2006.07.058 BindingDB Entry DOI: 10.7270/Q228076K
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50192635 (5,6-difluoro-N-((1R,3R,6R)-6-(3-((4-methylpiperazi...) Show SMILES CN1CCN(CCCN([C@@H]2CC[C@@]3(C[C@@H]3C2)c2cccc(CN3CCN(C)CC3)c2)c2nc3cc(F)c(F)cc3[nH]2)CC1 Show InChI InChI=1S/C34H47F2N7/c1-39-11-15-41(16-12-39)9-4-10-43(33-37-31-21-29(35)30(36)22-32(31)38-33)28-7-8-34(23-27(34)20-28)26-6-3-5-25(19-26)24-42-17-13-40(2)14-18-42/h3,5-6,19,21-22,27-28H,4,7-18,20,23-24H2,1-2H3,(H,37,38)/t27-,28+,34+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
University of Science and Technology Curated by ChEMBL					Assay Description Antagonist activity at MCHR1 (unknown origin) expressed in CHO cells co-expressing aequorin incubated for 10 mins by luminescence assay				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126741 BindingDB Entry DOI: 10.7270/Q2GH9NDS
					More data for this Ligand-Target Pair