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Found 1 hit Enz. Inhib. hit(s) with Target = 'Melanin-concentrating hormone receptor 1' and Ligand = 'BDBM50193686'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanin-concentrating hormone receptor 1


(RAT)		BDBM50193686
PNG
(1-{6-[6-(trifluoromethyl)pyridine-3-amido]quinolin...)
Show SMILES FC(F)(F)c1ccc(cn1)C(=O)Nc1ccc2nc(ccc2c1)[N+]12CCC(CC1)CC2
Show InChI InChI=1S/C23H21F3N4O/c24-23(25,26)20-5-1-17(14-27-20)22(31)28-18-3-4-19-16(13-18)2-6-21(29-19)30-10-7-15(8-11-30)9-12-30/h1-6,13-15H,7-12H2/p+1
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UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Stimulation of IP3-coupled mobilization of calcium in HEK293 cells expressing rat MCH-R1

Bioorg Med Chem Lett 16: 5270-4 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.006
BindingDB Entry DOI: 10.7270/Q2ZC82HP
More data for this
Ligand-Target Pair