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Found 1 hit Enz. Inhib. hit(s) with Target = 'Melanin-concentrating hormone receptor 1' and Ligand = 'BDBM50199242'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50199242
PNG
(6-(4-cyano)-3-[2-(4-morpholinylmethyl)-6-quinoliny...)
Show SMILES O=c1n(cnc2cc(sc12)-c1ccc(cc1)C#N)-c1ccc2nc(CN3CCOCC3)ccc2c1
Show InChI InChI=1S/C27H21N5O2S/c28-15-18-1-3-19(4-2-18)25-14-24-26(35-25)27(33)32(17-29-24)22-7-8-23-20(13-22)5-6-21(30-23)16-31-9-11-34-12-10-31/h1-8,13-14,17H,9-12,16H2
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n/an/a 478n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity against human MCHR1 expressed in CHO cells by Gal4/Elk1-Luc reporter assay

J Med Chem 49: 7095-107 (2006)


Article DOI: 10.1021/jm060572f
BindingDB Entry DOI: 10.7270/Q2P26XS8
More data for this
Ligand-Target Pair