Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Melanin-concentrating hormone receptor 1' and Ligand = 'BDBM50207671'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50207671 (CHEMBL247688 | N-(1-(4-(3-methoxy-3-methylbutoxy)b...) Show SMILES COC(C)(C)CCOc1ccc(CN2CCC(CC2)NC(=O)c2cc(=O)c3ccc(F)cc3o2)cc1 Show InChI InChI=1S/C28H33FN2O5/c1-28(2,34-3)12-15-35-22-7-4-19(5-8-22)18-31-13-10-21(11-14-31)30-27(33)26-17-24(32)23-9-6-20(29)16-25(23)36-26/h4-9,16-17,21H,10-15,18H2,1-3H3,(H,30,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	165	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]MCH from MCHR1 expressed in IMR32 cells				Bioorg Med Chem Lett 17: 2365-71 (2007) Article DOI: 10.1016/j.bmcl.2006.11.068 BindingDB Entry DOI: 10.7270/Q2N29WNW
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50207671 (CHEMBL247688 | N-(1-(4-(3-methoxy-3-methylbutoxy)b...) Show SMILES COC(C)(C)CCOc1ccc(CN2CCC(CC2)NC(=O)c2cc(=O)c3ccc(F)cc3o2)cc1 Show InChI InChI=1S/C28H33FN2O5/c1-28(2,34-3)12-15-35-22-7-4-19(5-8-22)18-31-13-10-21(11-14-31)30-27(33)26-17-24(32)23-9-6-20(29)16-25(23)36-26/h4-9,16-17,21H,10-15,18H2,1-3H3,(H,30,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Antagonist activity at MCHR1 assessed as inhibition of MCH-mediated calcium release in IMR32 cells				Bioorg Med Chem Lett 17: 2365-71 (2007) Article DOI: 10.1016/j.bmcl.2006.11.068 BindingDB Entry DOI: 10.7270/Q2N29WNW
					More data for this Ligand-Target Pair