Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Melanin-concentrating hormone receptor 1' and Ligand = 'BDBM50207683'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50207683 (CHEMBL245846 | N-(1-(3-fluoro-4-((2-(pyrrolidin-1-...) Show SMILES Fc1ccc2c(c1)oc(cc2=O)C(=O)NC1CCN(Cc2ccc(C(=O)NCCN3CCCC3)c(F)c2)CC1 Show InChI InChI=1S/C29H32F2N4O4/c30-20-4-6-23-25(36)17-27(39-26(23)16-20)29(38)33-21-7-12-35(13-8-21)18-19-3-5-22(24(31)15-19)28(37)32-9-14-34-10-1-2-11-34/h3-6,15-17,21H,1-2,7-14,18H2,(H,32,37)(H,33,38)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]MCH from MCHR1 expressed in IMR32 cells				Bioorg Med Chem Lett 17: 2365-71 (2007) Article DOI: 10.1016/j.bmcl.2006.11.068 BindingDB Entry DOI: 10.7270/Q2N29WNW
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50207683 (CHEMBL245846 | N-(1-(3-fluoro-4-((2-(pyrrolidin-1-...) Show SMILES Fc1ccc2c(c1)oc(cc2=O)C(=O)NC1CCN(Cc2ccc(C(=O)NCCN3CCCC3)c(F)c2)CC1 Show InChI InChI=1S/C29H32F2N4O4/c30-20-4-6-23-25(36)17-27(39-26(23)16-20)29(38)33-21-7-12-35(13-8-21)18-19-3-5-22(24(31)15-19)28(37)32-9-14-34-10-1-2-11-34/h3-6,15-17,21H,1-2,7-14,18H2,(H,32,37)(H,33,38)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Antagonist activity at MCHR1 assessed as inhibition of MCH-mediated calcium release in IMR32 cells				Bioorg Med Chem Lett 17: 2365-71 (2007) Article DOI: 10.1016/j.bmcl.2006.11.068 BindingDB Entry DOI: 10.7270/Q2N29WNW
					More data for this Ligand-Target Pair