Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 4' and Ligand = 'BDBM50124776'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50124776 ((S)-2-[(S)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...) Show SMILES CCCC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O Show InChI InChI=1S/C38H50N12O7/c1-2-6-33(53)47-31(17-24-19-42-21-46-24)37(57)49-29(15-22-10-12-25(51)13-11-22)36(56)48-28(9-5-14-43-38(40)41)35(55)50-30(34(54)45-20-32(39)52)16-23-18-44-27-8-4-3-7-26(23)27/h3-4,7-8,10-13,18-19,21,28-31,44,51H,2,5-6,9,14-17,20H2,1H3,(H2,39,52)(H,42,46)(H,45,54)(H,47,53)(H,48,56)(H,49,57)(H,50,55)(H4,40,41,43)/t28-,29-,30-,31-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.15E+3	n/a	n/a	n/a	n/a
Roche Research Center Curated by ChEMBL					Assay Description Effective concentration against hMC4R using HEK293 cells was determined by measuring cAMP accumulation				Bioorg Med Chem Lett 13: 649-52 (2003) BindingDB Entry DOI: 10.7270/Q2V69J0G
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