BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 4' and Ligand = 'BDBM50164775'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50164775 ((2S,5S)-5-tert-Butyl-piperazine-2-carboxylic acid ...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibitory concentration to displace [125I]NDP-alpha-MSH from human melanocortin 4 receptor expressed in CHO cells; Control 19 nM				Bioorg Med Chem Lett 15: 1993-6 (2005) Article DOI: 10.1016/j.bmcl.2005.02.068 BindingDB Entry DOI: 10.7270/Q2MK6DNT
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50164775 ((2S,5S)-5-tert-Butyl-piperazine-2-carboxylic acid ...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Concentration of compound at 50% maximum cAMP accumulation mediated by human melanocortin 4 receptor				Bioorg Med Chem Lett 15: 1993-6 (2005) Article DOI: 10.1016/j.bmcl.2005.02.068 BindingDB Entry DOI: 10.7270/Q2MK6DNT
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair