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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 4' and Ligand = 'BDBM50174259'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))		BDBM50174259
PNG
(CHEMBL197435 | N-((R)-1-(4-chloro-benzyl)-2-oxo-2-...)
Show SMILES Clc1ccc(C[C@@H](NC(=O)Cc2cccs2)C(=O)N2CCN(CC2)C2(CNC(=O)Cc3ccccc3)CCCCC2)cc1
Show InChI InChI=1S/C34H41ClN4O3S/c35-28-13-11-27(12-14-28)22-30(37-32(41)24-29-10-7-21-43-29)33(42)38-17-19-39(20-18-38)34(15-5-2-6-16-34)25-36-31(40)23-26-8-3-1-4-9-26/h1,3-4,7-14,21,30H,2,5-6,15-20,22-25H2,(H,36,40)(H,37,41)/t30-/m1/s1
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Similars
Article
PubMed
 80n/an/an/an/an/an/an/an/a



Neurocrine Biosciences Inc.

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cells

Bioorg Med Chem Lett 15: 5237-40 (2005)


Article DOI: 10.1016/j.bmcl.2005.08.061
BindingDB Entry DOI: 10.7270/Q2794476
More data for this
Ligand-Target Pair