BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 4' and Ligand = 'BDBM50186905'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))		BDBM50186905
PNG
((R)-1-((2-(4-(2-(3-aminopropanamido)-3-(2,4-dichlo...)
Show SMILES NCCC(=O)N[C@H](Cc1ccc(Cl)cc1Cl)C(=O)N1CCN(CC1)c1ncccc1CNC(=O)NCc1cccs1
Show InChI InChI=1S/C28H33Cl2N7O3S/c29-21-6-5-19(23(30)16-21)15-24(35-25(38)7-8-31)27(39)37-12-10-36(11-13-37)26-20(3-1-9-32-26)17-33-28(40)34-18-22-4-2-14-41-22/h1-6,9,14,16,24H,7-8,10-13,15,17-18,31H2,(H,35,38)(H2,33,34,40)/t24-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 750n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cells

Bioorg Med Chem Lett 16: 3693-6 (2006)


Article DOI: 10.1016/j.bmcl.2006.04.069
BindingDB Entry DOI: 10.7270/Q2NZ878P
More data for this
Ligand-Target Pair