Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 4' and Ligand = 'BDBM50189185'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50189185 ((S)-1-(4-(2-(1-amino-3-methylbutyl)-4-(trifluorome...) Show SMILES CC(C)C[C@H](N)c1cc(ccc1N1CCN(CC1)C(=O)CCc1ccc(O)cc1)C(F)(F)F Show InChI InChI=1S/C25H32F3N3O2/c1-17(2)15-22(29)21-16-19(25(26,27)28)6-9-23(21)30-11-13-31(14-12-30)24(33)10-5-18-3-7-20(32)8-4-18/h3-4,6-9,16-17,22,32H,5,10-15,29H2,1-2H3/t22-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Activity at MC4R assessed as inhibition of alpha-MSH-stimulated cAMP production				Bioorg Med Chem Lett 16: 4674-8 (2006) Article DOI: 10.1016/j.bmcl.2006.05.088 BindingDB Entry DOI: 10.7270/Q2C53KFR
					More data for this Ligand-Target Pair