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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 4' and Ligand = 'BDBM50189212'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))		BDBM50189212
PNG
(CHEMBL212553 | N-((1S)-1-(2-(4-(3-(2,4-dichlorophe...)
Show SMILES CCC(C)[C@H](NS(C)(=O)=O)c1cc(ccc1N1CCN(CC1)C(=O)CCc1ccc(Cl)cc1Cl)C(F)(F)F
Show InChI InChI=1S/C26H32Cl2F3N3O3S/c1-4-17(2)25(32-38(3,36)37)21-15-19(26(29,30)31)7-9-23(21)33-11-13-34(14-12-33)24(35)10-6-18-5-8-20(27)16-22(18)28/h5,7-9,15-17,25,32H,4,6,10-14H2,1-3H3/t17?,25-/m0/s1
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Similars
Article
PubMed
 1.80E+3n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Activity at MC4R assessed as inhibition of alpha-MSH-stimulated cAMP production

Bioorg Med Chem Lett 16: 4674-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.05.088
BindingDB Entry DOI: 10.7270/Q2C53KFR
More data for this
Ligand-Target Pair