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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 4' and Ligand = 'BDBM50189220'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))		BDBM50189220
PNG
(3-(2,4-dichlorophenyl)-1-(4-(2-((1S)-2-methyl-1-(2...)
Show SMILES CCC(C)CN[C@@H](C(C)CC)c1cc(ccc1N1CCN(CC1)C(=O)CCc1ccc(Cl)cc1Cl)C(F)(F)F
Show InChI InChI=1S/C30H40Cl2F3N3O/c1-5-20(3)19-36-29(21(4)6-2)25-17-23(30(33,34)35)9-11-27(25)37-13-15-38(16-14-37)28(39)12-8-22-7-10-24(31)18-26(22)32/h7,9-11,17-18,20-21,29,36H,5-6,8,12-16,19H2,1-4H3/t20?,21?,29-/m0/s1
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Similars
Article
PubMed
 2.80E+3n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Activity at MC4R assessed as inhibition of alpha-MSH-stimulated cAMP production

Bioorg Med Chem Lett 16: 4674-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.05.088
BindingDB Entry DOI: 10.7270/Q2C53KFR
More data for this
Ligand-Target Pair