Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 4' and Ligand = 'BDBM50189229'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50189229 (1-(4-(2-(1-amino-2-methylpropyl)-4-(trifluoromethy...) Show SMILES CC(C)C(N)c1cc(ccc1N1CCN(CC1)C(=O)CCc1ccc(Cl)cc1Cl)C(F)(F)F Show InChI InChI=1S/C24H28Cl2F3N3O/c1-15(2)23(30)19-13-17(24(27,28)29)5-7-21(19)31-9-11-32(12-10-31)22(33)8-4-16-3-6-18(25)14-20(16)26/h3,5-7,13-15,23H,4,8-12,30H2,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Activity at MC4R assessed as inhibition of alpha-MSH-stimulated cAMP production				Bioorg Med Chem Lett 16: 4674-8 (2006) Article DOI: 10.1016/j.bmcl.2006.05.088 BindingDB Entry DOI: 10.7270/Q2C53KFR
					More data for this Ligand-Target Pair