BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 4' and Ligand = 'BDBM50218075'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50218075 (CHEMBL248435 \| N-((S)-1-(2-(4-((3R,4S)-3-(4-chloro...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 5165-70 (2007) Article DOI: 10.1016/j.bmcl.2007.06.088 BindingDB Entry DOI: 10.7270/Q20R9P37
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50218075 (CHEMBL248435 \| N-((S)-1-(2-(4-((3R,4S)-3-(4-chloro...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	91	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Agonist activity at human MC4R expressed in HEK293 cells assessed as cAMP accumulation				Bioorg Med Chem Lett 17: 5165-70 (2007) Article DOI: 10.1016/j.bmcl.2007.06.088 BindingDB Entry DOI: 10.7270/Q20R9P37
Neurocrine Biosciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair