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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 4' and Ligand = 'BDBM50218078'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))		BDBM50218078
PNG
(((3S,4R)-4-(4-chlorophenyl)-1-isopropylpyrrolidin-...)
Show SMILES CC(C)N1C[C@H]([C@@H](C1)c1ccc(Cl)cc1)C(=O)N1CCN(CC1)c1ccccc1CNc1cccnc1
Show InChI InChI=1S/C30H36ClN5O/c1-22(2)36-20-27(23-9-11-25(31)12-10-23)28(21-36)30(37)35-16-14-34(15-17-35)29-8-4-3-6-24(29)18-33-26-7-5-13-32-19-26/h3-13,19,22,27-28,33H,14-18,20-21H2,1-2H3/t27-,28+/m0/s1
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Similars
Article
PubMed
 1.60E+3n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cells

Bioorg Med Chem Lett 17: 5165-70 (2007)


Article DOI: 10.1016/j.bmcl.2007.06.088
BindingDB Entry DOI: 10.7270/Q20R9P37
More data for this
Ligand-Target Pair