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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 4' and Ligand = 'BDBM50218108'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))		BDBM50218108
PNG
(CHEMBL250797 | [(3S,4R)-4-(4-chloro-phenyl)-1-isop...)
Show SMILES CC(C)N1C[C@H]([C@@H](C1)c1ccc(Cl)cc1)C(=O)N1CCN(CC1)c1ccccc1Cn1cncn1
Show InChI InChI=1S/C27H33ClN6O/c1-20(2)33-16-24(21-7-9-23(28)10-8-21)25(17-33)27(35)32-13-11-31(12-14-32)26-6-4-3-5-22(26)15-34-19-29-18-30-34/h3-10,18-20,24-25H,11-17H2,1-2H3/t24-,25+/m0/s1
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PC sid
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Similars
Article
PubMed
 320n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cells

Bioorg Med Chem Lett 17: 5165-70 (2007)


Article DOI: 10.1016/j.bmcl.2007.06.088
BindingDB Entry DOI: 10.7270/Q20R9P37
More data for this
Ligand-Target Pair