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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 4' and Ligand = 'BDBM50235780'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))		BDBM50235780
PNG
((4-(2-((S)-1-amino-2-methylpropyl)-6-fluorophenyl)...)
Show SMILES CC(C)[C@H](N)c1cccc(F)c1N1CCN(CC1)C(=O)C1NCCC1c1ccc(Cl)cc1Cl |w:24.27,20.21|
Show InChI InChI=1S/C25H31Cl2FN4O/c1-15(2)22(29)19-4-3-5-21(28)24(19)31-10-12-32(13-11-31)25(33)23-18(8-9-30-23)17-7-6-16(26)14-20(17)27/h3-7,14-15,18,22-23,30H,8-13,29H2,1-2H3/t18?,22-,23?/m0/s1
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Similars
Article
PubMed
 560n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Displacement of [125]NDPMSH from human MC4 receptor expressed in HEK293 cells

Bioorg Med Chem Lett 18: 1931-8 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.125
BindingDB Entry DOI: 10.7270/Q2WD409C
More data for this
Ligand-Target Pair