Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 4' and Ligand = 'BDBM50253737'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50253737 (CHEMBL453300 | N-((R)-3-(4-Fluorophenyl)-1-((S)-4-...) Show SMILES CCC[C@@H]1N(CCN([C@@H](Cc2ccc3ccccc3c2)C(=O)NC)C1=O)C(=O)[C@@H](Cc1ccc(F)cc1)NC(=O)c1cscn1 |r| Show InChI InChI=1S/C34H36FN5O4S/c1-3-6-29-34(44)40(30(32(42)36-2)19-23-9-12-24-7-4-5-8-25(24)17-23)16-15-39(29)33(43)27(18-22-10-13-26(35)14-11-22)38-31(41)28-20-45-21-37-28/h4-5,7-14,17,20-21,27,29-30H,3,6,15-16,18-19H2,1-2H3,(H,36,42)(H,38,41)/t27-,29+,30+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of europium-labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cells				J Med Chem 51: 6055-66 (2008) Article DOI: 10.1021/jm800525p BindingDB Entry DOI: 10.7270/Q2DV1JQC
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50253737 (CHEMBL453300 | N-((R)-3-(4-Fluorophenyl)-1-((S)-4-...) Show SMILES CCC[C@@H]1N(CCN([C@@H](Cc2ccc3ccccc3c2)C(=O)NC)C1=O)C(=O)[C@@H](Cc1ccc(F)cc1)NC(=O)c1cscn1 |r| Show InChI InChI=1S/C34H36FN5O4S/c1-3-6-29-34(44)40(30(32(42)36-2)19-23-9-12-24-7-4-5-8-25(24)17-23)16-15-39(29)33(43)27(18-22-10-13-26(35)14-11-22)38-31(41)28-20-45-21-37-28/h4-5,7-14,17,20-21,27,29-30H,3,6,15-16,18-19H2,1-2H3,(H,36,42)(H,38,41)/t27-,29+,30+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	37	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human MC4R expressed in HEK293 cells assessed as effect on CRE-driven luminescence by luciferase reporter gene assay				J Med Chem 51: 6055-66 (2008) Article DOI: 10.1021/jm800525p BindingDB Entry DOI: 10.7270/Q2DV1JQC
					More data for this Ligand-Target Pair