Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 4' and Ligand = 'BDBM50348577'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50348577 (CHEMBL1801149) Show SMILES Cc1cc2[C@H](CC3(CCN(CC3)C(=O)[C@@H]3CN(C[C@H]3c3ccc(F)cc3F)C(C)(C)C)c2cc1Cl)C(C)(C)C(=O)N1CC[C@@H](F)C1 |r| Show InChI InChI=1S/C37H47ClF3N3O2/c1-22-15-26-29(17-31(22)38)37(18-30(26)36(5,6)34(46)43-12-9-24(40)19-43)10-13-42(14-11-37)33(45)28-21-44(35(2,3)4)20-27(28)25-8-7-23(39)16-32(25)41/h7-8,15-17,24,27-28,30H,9-14,18-21H2,1-6H3/t24-,27+,28-,30+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]-NDP-R-MSH from human MC4R expressed in CHO cells after 1.5 hrs by scintillation counting				Bioorg Med Chem Lett 20: 4399-405 (2010) Article DOI: 10.1016/j.bmcl.2010.06.062 BindingDB Entry DOI: 10.7270/Q23F4Q07
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50348577 (CHEMBL1801149) Show SMILES Cc1cc2[C@H](CC3(CCN(CC3)C(=O)[C@@H]3CN(C[C@H]3c3ccc(F)cc3F)C(C)(C)C)c2cc1Cl)C(C)(C)C(=O)N1CC[C@@H](F)C1 |r| Show InChI InChI=1S/C37H47ClF3N3O2/c1-22-15-26-29(17-31(22)38)37(18-30(26)36(5,6)34(46)43-12-9-24(40)19-43)10-13-42(14-11-37)33(45)28-21-44(35(2,3)4)20-27(28)25-8-7-23(39)16-32(25)41/h7-8,15-17,24,27-28,30H,9-14,18-21H2,1-6H3/t24-,27+,28-,30+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human MC4R expressed in CHO cells assessed as increase of alpha-MSH-stimulated cAMP release pretreated for 10 mins before alpha-M...				Bioorg Med Chem Lett 20: 4399-405 (2010) Article DOI: 10.1016/j.bmcl.2010.06.062 BindingDB Entry DOI: 10.7270/Q23F4Q07
					More data for this Ligand-Target Pair