Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Melanocortin receptor 5' and Ligand = 'BDBM50112888'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 5 (Homo sapiens (Human))	BDBM50112888 (CHEMBL3600737) Show SMILES CCCC[C@@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](N(C)C(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O |r| Show InChI InChI=1S/C55H73N15O9/c1-4-5-16-40(64-32(2)71)49(74)68-44-28-47(72)60-22-11-10-19-46(48(56)73)70(3)54(79)45(26-36-29-62-39-17-9-8-15-38(36)39)69-50(75)41(18-12-23-61-55(57)58)65-51(76)42(25-33-20-21-34-13-6-7-14-35(34)24-33)66-52(77)43(67-53(44)78)27-37-30-59-31-63-37/h6-9,13-15,17,20-21,24,29-31,40-46,62H,4-5,10-12,16,18-19,22-23,25-28H2,1-3H3,(H2,56,73)(H,59,63)(H,60,72)(H,64,71)(H,65,76)(H,66,77)(H,67,78)(H,68,74)(H,69,75)(H4,57,58,61)/t40-,41+,42-,43+,44+,45+,46+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Displacement of [125I]-[Nle4,D-Phe7]-alpha-MSH from human MC5 receptor expressed in HEK293 cells after 40 mins by luminescence counting				J Med Chem 58: 6359-67 (2015) Article DOI: 10.1021/acs.jmedchem.5b00102 BindingDB Entry DOI: 10.7270/Q251410F
					More data for this Ligand-Target Pair
Melanocortin receptor 5 (Homo sapiens (Human))	BDBM50112888 (CHEMBL3600737) Show SMILES CCCC[C@@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](N(C)C(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O |r| Show InChI InChI=1S/C55H73N15O9/c1-4-5-16-40(64-32(2)71)49(74)68-44-28-47(72)60-22-11-10-19-46(48(56)73)70(3)54(79)45(26-36-29-62-39-17-9-8-15-38(36)39)69-50(75)41(18-12-23-61-55(57)58)65-51(76)42(25-33-20-21-34-13-6-7-14-35(34)24-33)66-52(77)43(67-53(44)78)27-37-30-59-31-63-37/h6-9,13-15,17,20-21,24,29-31,40-46,62H,4-5,10-12,16,18-19,22-23,25-28H2,1-3H3,(H2,56,73)(H,59,63)(H,60,72)(H,64,71)(H,65,76)(H,66,77)(H,67,78)(H,68,74)(H,69,75)(H4,57,58,61)/t40-,41+,42-,43+,44+,45+,46+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	60	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Agonist activity at human MC5 receptor expressed in HEK293 cells assessed as intracellular cAMP accumulation using [3H]-cAMP by luminescence counting				J Med Chem 58: 6359-67 (2015) Article DOI: 10.1021/acs.jmedchem.5b00102 BindingDB Entry DOI: 10.7270/Q251410F
					More data for this Ligand-Target Pair