Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Melanocyte-stimulating hormone receptor' and Ligand = 'BDBM50468287'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocyte-stimulating hormone receptor (Homo sapiens (Human))	BDBM50468287 (CHEMBL4292317) Show SMILES CCCC[C@H](NC(=O)[C@@H](Cc1ccc(F)cc1)NC(=O)[C@@H]1CCCN1C(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |r| Show InChI InChI=1S/C33H41FN6O5/c1-3-4-9-26(31(43)38-27(30(35)42)18-22-19-36-25-10-6-5-8-24(22)25)37-32(44)28(17-21-12-14-23(34)15-13-21)39-33(45)29-11-7-16-40(29)20(2)41/h5-6,8,10,12-15,19,26-29,36H,3-4,7,9,11,16-18H2,1-2H3,(H2,35,42)(H,37,44)(H,38,43)(H,39,45)/t26-,27-,28+,29-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.740	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Displacement of [125I]-[Nle4,d-Phe7]-alpha-MSH from human MC1R expressed in HEK293 cells after 40 mins by gamma counting analysis				Eur J Med Chem 151: 815-823 (2018) Article DOI: 10.1016/j.ejmech.2018.04.021 BindingDB Entry DOI: 10.7270/Q20K2C9T
					More data for this Ligand-Target Pair
Melanocyte-stimulating hormone receptor (Homo sapiens (Human))	BDBM50468287 (CHEMBL4292317) Show SMILES CCCC[C@H](NC(=O)[C@@H](Cc1ccc(F)cc1)NC(=O)[C@@H]1CCCN1C(C)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |r| Show InChI InChI=1S/C33H41FN6O5/c1-3-4-9-26(31(43)38-27(30(35)42)18-22-19-36-25-10-6-5-8-24(22)25)37-32(44)28(17-21-12-14-23(34)15-13-21)39-33(45)29-11-7-16-40(29)20(2)41/h5-6,8,10,12-15,19,26-29,36H,3-4,7,9,11,16-18H2,1-2H3,(H2,35,42)(H,37,44)(H,38,43)(H,39,45)/t26-,27-,28+,29-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Agonist activity at human MC1R expressed in HEK293 cells after 3 mins by cAMP assay				Eur J Med Chem 151: 815-823 (2018) Article DOI: 10.1016/j.ejmech.2018.04.021 BindingDB Entry DOI: 10.7270/Q20K2C9T
					More data for this Ligand-Target Pair