Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Menin' and Ligand = 'BDBM50516560'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Menin (Homo sapiens (Human))	BDBM50516560 (CHEMBL4592512 | US10899738, Cpd. No 132) Show SMILES CS(=O)(=O)c1ccc(cc1)N1CC(CN2CCC(CC2)C2(NCCc3ccccc23)C2CCCC2)C1 Show InChI InChI=1S/C30H41N3O2S/c1-36(34,35)28-12-10-27(11-13-28)33-21-23(22-33)20-32-18-15-26(16-19-32)30(25-7-3-4-8-25)29-9-5-2-6-24(29)14-17-31-30/h2,5-6,9-13,23,25-26,31H,3-4,7-8,14-22H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516560 (CHEMBL4592512 | US10899738, Cpd. No 132) Show SMILES CS(=O)(=O)c1ccc(cc1)N1CC(CN2CCC(CC2)C2(NCCc3ccccc23)C2CCCC2)C1 Show InChI InChI=1S/C30H41N3O2S/c1-36(34,35)28-12-10-27(11-13-28)33-21-23(22-33)20-32-18-15-26(16-19-32)30(25-7-3-4-8-25)29-9-5-2-6-24(29)14-17-31-30/h2,5-6,9-13,23,25-26,31H,3-4,7-8,14-22H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
THE REGENTS OF THE UNIVERSITY OF MICHIGAN US Patent					Assay Description A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...				US Patent US10899738 (2021) BindingDB Entry DOI: 10.7270/Q28K7D5T
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50516560 (CHEMBL4592512 | US10899738, Cpd. No 132) Show SMILES CS(=O)(=O)c1ccc(cc1)N1CC(CN2CCC(CC2)C2(NCCc3ccccc23)C2CCCC2)C1 Show InChI InChI=1S/C30H41N3O2S/c1-36(34,35)28-12-10-27(11-13-28)33-21-23(22-33)20-32-18-15-26(16-19-32)30(25-7-3-4-8-25)29-9-5-2-6-24(29)14-17-31-30/h2,5-6,9-13,23,25-26,31H,3-4,7-8,14-22H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	143	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assay				J Med Chem 62: 6015-6034 (2019) Article DOI: 10.1021/acs.jmedchem.9b00021 BindingDB Entry DOI: 10.7270/Q2P84G8G
					More data for this Ligand-Target Pair