Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 1' and Ligand = 'BDBM50034501'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50034501 ((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...) Show SMILES N[C@H](C(O)=O)c1cc(=O)[nH]o1 Show InChI InChI=1S/C5H6N2O4/c6-4(5(9)10)2-1-3(8)7-11-2/h1,4H,6H2,(H,7,8)(H,9,10)/t4-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a
Università di Perugia Curated by ChEMBL					Assay Description Effective concentration of the compound for half maximal stimulation of PI hydrolysis (mGluR1a)				J Med Chem 39: 3998-4006 (1996) Article DOI: 10.1021/jm9601718 BindingDB Entry DOI: 10.7270/Q2765DFJ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50034501 ((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...) Show SMILES N[C@H](C(O)=O)c1cc(=O)[nH]o1 Show InChI InChI=1S/C5H6N2O4/c6-4(5(9)10)2-1-3(8)7-11-2/h1,4H,6H2,(H,7,8)(H,9,10)/t4-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	4.40E+4	n/a	n/a	n/a	n/a
CNS Research Curated by ChEMBL					Assay Description Concentration for half maximal activation of metabotropic glutamate mGluR1b in rat				J Med Chem 38: 1417-26 (1995) BindingDB Entry DOI: 10.7270/Q20R9Q1R
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50034501 ((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...) Show SMILES N[C@H](C(O)=O)c1cc(=O)[nH]o1 Show InChI InChI=1S/C5H6N2O4/c6-4(5(9)10)2-1-3(8)7-11-2/h1,4H,6H2,(H,7,8)(H,9,10)/t4-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	4.30E+4	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Activity at rat cloned mGluR1a expressed in CHO cells assessed as effect on cAMP accumulation				J Med Chem 51: 2311-5 (2008) Article DOI: 10.1021/jm701394a BindingDB Entry DOI: 10.7270/Q2Z320HT
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50034501 ((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...) Show SMILES N[C@H](C(O)=O)c1cc(=O)[nH]o1 Show InChI InChI=1S/C5H6N2O4/c6-4(5(9)10)2-1-3(8)7-11-2/h1,4H,6H2,(H,7,8)(H,9,10)/t4-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a
CNS Research Curated by ChEMBL					Assay Description Concentration for half maximal activation of metabotropic glutamate mGluR1c in rat				J Med Chem 38: 1417-26 (1995) BindingDB Entry DOI: 10.7270/Q20R9Q1R
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50034501 ((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...) Show SMILES N[C@H](C(O)=O)c1cc(=O)[nH]o1 Show InChI InChI=1S/C5H6N2O4/c6-4(5(9)10)2-1-3(8)7-11-2/h1,4H,6H2,(H,7,8)(H,9,10)/t4-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a
CNS Research Curated by ChEMBL					Assay Description Concentration for half maximal activation of metabotropic glutamate mGluR1a in rat				J Med Chem 38: 1417-26 (1995) BindingDB Entry DOI: 10.7270/Q20R9Q1R
					More data for this Ligand-Target Pair