Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 1' and Ligand = 'BDBM50278291'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 1 (RAT)	BDBM50278291 (CHEMBL471666 | N-cyclohexyl-6-(2-methoxyethoxy)pyr...) Show SMILES COCCOc1cc2c(NC3CCCCC3)ncnc2cn1 Show InChI InChI=1S/C16H22N4O2/c1-21-7-8-22-15-9-13-14(10-17-15)18-11-19-16(13)20-12-5-3-2-4-6-12/h9-12H,2-8H2,1H3,(H,18,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	101	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical Research Council Technology Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...				Bioorg Med Chem Lett 19: 2190-4 (2009) Article DOI: 10.1016/j.bmcl.2009.02.106 BindingDB Entry DOI: 10.7270/Q2057FSP
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