Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 1' and Ligand = 'BDBM50296683'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 1 (RAT)	BDBM50296683 (4-(5-pentylpyridin-2-yl)phenyl 4-ethylcyclohexanec...) Show SMILES CCCCCc1ccc(nc1)-c1ccc(OC(=O)C2CCC(CC)CC2)cc1 |(3.83,-46.98,;5.37,-46.96,;6.12,-45.61,;7.66,-45.59,;8.41,-44.24,;9.95,-44.22,;10.7,-42.87,;12.24,-42.84,;13.04,-44.16,;12.29,-45.51,;10.74,-45.54,;14.57,-44.13,;15.36,-45.45,;16.9,-45.42,;17.65,-44.08,;19.19,-44.05,;19.98,-45.36,;21.52,-45.33,;19.24,-46.71,;17.7,-46.73,;16.96,-48.08,;17.75,-49.4,;17,-50.74,;15.46,-50.77,;19.29,-49.37,;20.04,-48.02,;16.84,-42.75,;15.31,-42.79,)| Show InChI InChI=1S/C25H33NO2/c1-3-5-6-7-20-10-17-24(26-18-20)21-13-15-23(16-14-21)28-25(27)22-11-8-19(4-2)9-12-22/h10,13-19,22H,3-9,11-12H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Pharmaceuticals GmbH Curated by ChEMBL					Assay Description Displacement of [3H]E-3-(2-chloro-8-methylquinolin-3-yl)-1-(thiophen-2-yl)prop-2-en-1-one from mGluR1 in rat cerebellar membrane after 14 to 16 hrs b...				Bioorg Med Chem 17: 5708-15 (2009) Article DOI: 10.1016/j.bmc.2009.05.072 BindingDB Entry DOI: 10.7270/Q2416X30
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50296683 (4-(5-pentylpyridin-2-yl)phenyl 4-ethylcyclohexanec...) Show SMILES CCCCCc1ccc(nc1)-c1ccc(OC(=O)C2CCC(CC)CC2)cc1 |(3.83,-46.98,;5.37,-46.96,;6.12,-45.61,;7.66,-45.59,;8.41,-44.24,;9.95,-44.22,;10.7,-42.87,;12.24,-42.84,;13.04,-44.16,;12.29,-45.51,;10.74,-45.54,;14.57,-44.13,;15.36,-45.45,;16.9,-45.42,;17.65,-44.08,;19.19,-44.05,;19.98,-45.36,;21.52,-45.33,;19.24,-46.71,;17.7,-46.73,;16.96,-48.08,;17.75,-49.4,;17,-50.74,;15.46,-50.77,;19.29,-49.37,;20.04,-48.02,;16.84,-42.75,;15.31,-42.79,)| Show InChI InChI=1S/C25H33NO2/c1-3-5-6-7-20-10-17-24(26-18-20)21-13-15-23(16-14-21)28-25(27)22-11-8-19(4-2)9-12-22/h10,13-19,22H,3-9,11-12H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merz Pharmaceuticals GmbH Curated by ChEMBL					Assay Description Allosteric antagonist activity at mGluR1 in Sprague-Dawley rat cerebellar granule cells assessed as accumulation of [3H]inositol phosphate by liquid ...				Bioorg Med Chem 17: 5708-15 (2009) Article DOI: 10.1016/j.bmc.2009.05.072 BindingDB Entry DOI: 10.7270/Q2416X30
					More data for this Ligand-Target Pair