Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 1' and Ligand = 'BDBM50296687'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 1 (RAT)	BDBM50296687 (1-(4-methoxyphenyl)-3-(4-(thietan-3-yloxy)phenyl)p...) Show SMILES COc1ccc(cc1)C(=O)\C=C\c1ccc(OC2CSC2)cc1 Show InChI InChI=1S/C19H18O3S/c1-21-16-9-5-15(6-10-16)19(20)11-4-14-2-7-17(8-3-14)22-18-12-23-13-18/h2-11,18H,12-13H2,1H3/b11-4+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Pharmaceuticals GmbH Curated by ChEMBL					Assay Description Displacement of [3H]E-3-(2-chloro-8-methylquinolin-3-yl)-1-(thiophen-2-yl)prop-2-en-1-one from mGluR1 in rat cerebellar membrane after 14 to 16 hrs b...				Bioorg Med Chem 17: 5708-15 (2009) Article DOI: 10.1016/j.bmc.2009.05.072 BindingDB Entry DOI: 10.7270/Q2416X30
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (RAT)	BDBM50296687 (1-(4-methoxyphenyl)-3-(4-(thietan-3-yloxy)phenyl)p...) Show SMILES COc1ccc(cc1)C(=O)\C=C\c1ccc(OC2CSC2)cc1 Show InChI InChI=1S/C19H18O3S/c1-21-16-9-5-15(6-10-16)19(20)11-4-14-2-7-17(8-3-14)22-18-12-23-13-18/h2-11,18H,12-13H2,1H3/b11-4+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merz Pharmaceuticals GmbH Curated by ChEMBL					Assay Description Allosteric antagonist activity at mGluR1 in Sprague-Dawley rat cerebellar granule cells assessed as accumulation of [3H]inositol phosphate by liquid ...				Bioorg Med Chem 17: 5708-15 (2009) Article DOI: 10.1016/j.bmc.2009.05.072 BindingDB Entry DOI: 10.7270/Q2416X30
					More data for this Ligand-Target Pair