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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 1' and Ligand = 'BDBM50422826'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 1


(RAT)		BDBM50422826
PNG
(CHEMBL377503)
Show SMILES CC(OC(=O)c1cn2CCN(CCF)C(=O)c2c1C)C(C)(C)C
Show InChI InChI=1S/C17H25FN2O3/c1-11-13(16(22)23-12(2)17(3,4)5)10-20-9-8-19(7-6-18)15(21)14(11)20/h10,12H,6-9H2,1-5H3
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 20n/an/an/an/an/an/a



GlaxoSmithKline Medicine Research Centre

Curated by ChEMBL


Assay Description
Inhibition of rat mGluR1a in CHO cells by CDP-DAG accumulation method

Bioorg Med Chem Lett 16: 1342-5 (2006)


Article DOI: 10.1016/j.bmcl.2005.11.049
BindingDB Entry DOI: 10.7270/Q25B03S5
More data for this
Ligand-Target Pair