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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Ligand = 'BDBM160723'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))		BDBM160723
PNG
(US9682980, 8-Chloro-3-neopentyl-7-(4-(pyrimidin-2-...)
Show SMILES CC(C)(C)Cc1nnc2c(Cl)c(cnn12)N1CCC(CC1)c1ncccn1
Show InChI InChI=1S/C19H24ClN7/c1-19(2,3)11-15-24-25-18-16(20)14(12-23-27(15)18)26-9-5-13(6-10-26)17-21-7-4-8-22-17/h4,7-8,12-13H,5-6,9-11H2,1-3H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 437n/an/a7.0n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Clonally expressed human mGluR2 in HEK293 background was glutamate starved overnight in media without glutamine (GIBCO MEM 12360), containing 10% FBS...

US Patent US9682980 (2017)


BindingDB Entry DOI: 10.7270/Q2J964JS
More data for this
Ligand-Target Pair