Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Ligand = 'BDBM252637'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM252637 (US9458176, 34) Show SMILES CCOc1ccc(cc1Cl)-c1nc(c2CCO[C@H](C)Cn12)-c1cc(C)nc(C)c1 |r| Show InChI InChI=1S/C23H26ClN3O2/c1-5-28-21-7-6-17(12-19(21)24)23-26-22(18-10-14(2)25-15(3)11-18)20-8-9-29-16(4)13-27(20)23/h6-7,10-12,16H,5,8-9,13H2,1-4H3/t16-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	25
Eisai R&D Management Co., Ltd. US Patent					Assay Description The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...				US Patent US9458176 (2016) BindingDB Entry DOI: 10.7270/Q2PK0F3D
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