Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Ligand = 'BDBM252846'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM252846 (US9458176, 243) Show SMILES CCOc1ccc(cc1C)-c1nc(c2CCO[C@H](CF)Cn12)-c1cc(C)nc(C)c1 |r| Show InChI InChI=1S/C24H28FN3O2/c1-5-29-22-7-6-18(10-15(22)2)24-27-23(19-11-16(3)26-17(4)12-19)21-8-9-30-20(13-25)14-28(21)24/h6-7,10-12,20H,5,8-9,13-14H2,1-4H3/t20-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	25
Eisai R&D Management Co., Ltd. US Patent					Assay Description The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...				US Patent US9458176 (2016) BindingDB Entry DOI: 10.7270/Q2PK0F3D
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