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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Ligand = 'BDBM50151455'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))		BDBM50151455
PNG
((1R,2R,3R,5R,6R)-2-Amino-6-fluoro-3-(3-trifluorome...)
Show SMILES N[C@@]1([C@H]2[C@@H](C[C@H]1OCc1cccc(c1)C(F)(F)F)[C@]2(F)C(O)=O)C(O)=O
Show InChI InChI=1S/C16H15F4NO5/c17-14(12(22)23)9-5-10(15(21,11(9)14)13(24)25)26-6-7-2-1-3-8(4-7)16(18,19)20/h1-4,9-11H,5-6,21H2,(H,22,23)(H,24,25)/t9-,10-,11+,14-,15+/m1/s1
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Similars
Article
PubMed
 5.72n/an/an/an/an/an/an/an/a



Taisho Pharmaceutical Co., Ltd.

Curated by ChEMBL


Assay Description
Binding affinity towards metabotropic glutamate receptor 2 of rat expressed in CHO cells was determined by using [3H]-MGS0008

J Med Chem 47: 4570-87 (2004)


Article DOI: 10.1021/jm0400294
BindingDB Entry DOI: 10.7270/Q2GH9HFK
More data for this
Ligand-Target Pair