Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Ligand = 'BDBM50274141'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50274141 (3-methyl-2-(((1R,5S)-6-(phenoxymethyl)-3-aza-bicyc...) Show SMILES Cn1c(CN2C[C@H]3C(COc4ccccc4)[C@H]3C2)nc2ccncc12 |r| Show InChI InChI=1S/C20H22N4O/c1-23-19-9-21-8-7-18(19)22-20(23)12-24-10-15-16(11-24)17(15)13-25-14-5-3-2-4-6-14/h2-9,15-17H,10-13H2,1H3/t15-,16+,17?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.12E+3	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Activity at rat mGluR2 receptor expressed in HEK cells by FLIPR assay in presence of glutamate				Bioorg Med Chem Lett 18: 5493-6 (2008) Article DOI: 10.1016/j.bmcl.2008.09.026 BindingDB Entry DOI: 10.7270/Q2P26XZH
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