Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 2' and Ligand = 'BDBM50332633'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50332633 (CHEMBL1630806 | N-(4-Methylphenyl)-7-oxo-7,7a-dihy...) Show SMILES Cc1ccc(NC(=O)C23CC2C(N=O)c2ccccc2O3)cc1 Show InChI InChI=1S/C18H16N2O3/c1-11-6-8-12(9-7-11)19-17(21)18-10-14(18)16(20-22)13-4-2-3-5-15(13)23-18/h2-9,14,16H,10H2,1H3,(H,19,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Domain Therapeutics SA Curated by ChEMBL					Assay Description Binding affinity to GFP tagged human mGluR2 containing truncated N-terminal region expressed in HEK cells by FRET assay				J Med Chem 53: 8775-9 (2010) Article DOI: 10.1021/jm101069m BindingDB Entry DOI: 10.7270/Q2WD40VJ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50332633 (CHEMBL1630806 | N-(4-Methylphenyl)-7-oxo-7,7a-dihy...) Show SMILES Cc1ccc(NC(=O)C23CC2C(N=O)c2ccccc2O3)cc1 Show InChI InChI=1S/C18H16N2O3/c1-11-6-8-12(9-7-11)19-17(21)18-10-14(18)16(20-22)13-4-2-3-5-15(13)23-18/h2-9,14,16H,10H2,1H3,(H,19,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Domain Therapeutics SA Curated by ChEMBL					Assay Description Negative allosteric modulator activity at human mGluR2 expressed in HEK cells in presence of glutamate EC80 concentration by Ca2+ functional assay				J Med Chem 53: 8775-9 (2010) Article DOI: 10.1021/jm101069m BindingDB Entry DOI: 10.7270/Q2WD40VJ
					More data for this Ligand-Target Pair