BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 3' and Ligand = 'BDBM393845'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 3


(Rattus norvegicus (Rat))		BDBM393845
PNG
(US10597367, Example 133 | US9969726, Example 133)
Show SMILES Fc1ccc(cc1-c1noc(=O)[nH]1)-c1cccc(c1)-c1nc(cc(n1)C(F)(F)F)-c1ccoc1
Show InChI InChI=1S/C23H12F4N4O3/c24-17-5-4-13(9-16(17)21-30-22(32)34-31-21)12-2-1-3-14(8-12)20-28-18(15-6-7-33-11-15)10-19(29-20)23(25,26)27/h1-11H,(H,30,31,32)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 330n/an/an/an/a



Universita degli Studi di Roma La Sapienza



Assay Description
Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...

J Med Chem 52: 1935-42 (2009)


BindingDB Entry DOI: 10.7270/Q2RX9FDX
More data for this
Ligand-Target Pair