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Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 3' and Ligand = 'BDBM50167034'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 3


(Homo sapiens (Human))
BDBM50167034
PNG
((1S,2S,4S,5R,6S)-2-Amino-4-methyl-bicyclo[3.1.0]he...)
Show SMILES C[C@H]1C[C@](N)([C@H]2[C@@H]1[C@@H]2C(O)=O)C(O)=O
Show InChI InChI=1S/C9H13NO4/c1-3-2-9(10,8(13)14)6-4(3)5(6)7(11)12/h3-6H,2,10H2,1H3,(H,11,12)(H,13,14)/t3-,4-,5-,6-,9-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
511n/an/an/an/an/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Displacement of [3H]-341495 binding to membranes expressing recombinant human Metabotropic glutamate receptor 3


J Med Chem 48: 3605-12 (2005)


Article DOI: 10.1021/jm040222y
BindingDB Entry DOI: 10.7270/Q2NS0TDR
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Homo sapiens (Human))
BDBM50167034
PNG
((1S,2S,4S,5R,6S)-2-Amino-4-methyl-bicyclo[3.1.0]he...)
Show SMILES C[C@H]1C[C@](N)([C@H]2[C@@H]1[C@@H]2C(O)=O)C(O)=O
Show InChI InChI=1S/C9H13NO4/c1-3-2-9(10,8(13)14)6-4(3)5(6)7(11)12/h3-6H,2,10H2,1H3,(H,11,12)(H,13,14)/t3-,4-,5-,6-,9-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 166n/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Agonist activity at human mGlu3 receptor expressed in golden Syrian hamster AV12 cells coexpressing EAAT1 after 20 mins by HTRF assay


J Med Chem 56: 4442-55 (2013)


Article DOI: 10.1021/jm4000165
BindingDB Entry DOI: 10.7270/Q20003G4
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 3


(Homo sapiens (Human))
BDBM50167034
PNG
((1S,2S,4S,5R,6S)-2-Amino-4-methyl-bicyclo[3.1.0]he...)
Show SMILES C[C@H]1C[C@](N)([C@H]2[C@@H]1[C@@H]2C(O)=O)C(O)=O
Show InChI InChI=1S/C9H13NO4/c1-3-2-9(10,8(13)14)6-4(3)5(6)7(11)12/h3-6H,2,10H2,1H3,(H,11,12)(H,13,14)/t3-,4-,5-,6-,9-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 34n/an/an/an/a



Eli Lilly and Company

Curated by ChEMBL


Assay Description
Evaluation of the functional effect on cAMP responses in RGT cells expressing human mGlu3 receptor


J Med Chem 48: 3605-12 (2005)


Article DOI: 10.1021/jm040222y
BindingDB Entry DOI: 10.7270/Q2NS0TDR
More data for this
Ligand-Target Pair