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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 4' and Ligand = 'BDBM50323569'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 4


(Homo sapiens (Human))
BDBM50323569
PNG
(4-(naphthalen-2-yl)pyrimidin-2-amine | CHEMBL12095...)
Show SMILES Nc1nccc(n1)-c1ccc2ccccc2c1
Show InChI InChI=1S/C14H11N3/c15-14-16-8-7-13(17-14)12-6-5-10-3-1-2-4-11(10)9-12/h1-9H,(H2,15,16,17)
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a>3.00E+4n/an/an/an/a



Evotec (UK) Ltd

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human mGluR4 expressed in CHO-K1 cells assessed as decrease in forskolin-induced intracellular cAMP accumulation af...


Bioorg Med Chem Lett 20: 4901-5 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.078
BindingDB Entry DOI: 10.7270/Q2X34XN7
More data for this
Ligand-Target Pair