Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Metabotropic glutamate receptor 5' and Ligand = 'BDBM50022778'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50022778 (CHEMBL3297927) Show SMILES Fc1cccc(COc2cnc3CCN(Cc3c2)C(=O)c2cccc(F)c2)c1 Show InChI InChI=1S/C22H18F2N2O2/c23-18-5-1-3-15(9-18)14-28-20-11-17-13-26(8-7-21(17)25-12-20)22(27)16-4-2-6-19(24)10-16/h1-6,9-12H,7-8,13-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.62E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulator activity at rat mGlu5 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...				J Med Chem 57: 5620-37 (2014) Article DOI: 10.1021/jm500259z BindingDB Entry DOI: 10.7270/Q2736SHB
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